The factors For picking Medication For any Patient

SINCE The second world war, medical science has progressed with a stage where competitive medications are for sale to treat the same ailment in various people. This is not pretty much brands (which is a trade issue) but generic drugs (which is a scientific issue). On this report, we shall look at the various factors that decide your selection of a certain drug.

Safety: The following sub-criteria must be considered underneath the criterion of safety:

* Acute therapeutic index: In the event the patient’s condition is acute, how effective is a particular drug regardless of whether it’s got certain side-effects providing the acuteness from the condition is lowered? Example: narcotic pain-killers are very effective in healing pain but include the potential side-effect of addiction.

* Long-term safety: medicine might be safe in short-term treatment, but exactly how safe it really is in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but sometimes have undesirable effects in case there is prolonged use.

* Drug-drug interaction risk: Medicines are chemicals, and lots of chemicals reply to develop a different chemical, which has an effect that could harm the individual or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to produce a new condition that warrants separate treatment.

Drug-drug interaction risk is of two types:

· Pharmacokinetic: In this kind of drug-drug interaction, two drugs, separate from the other, have certain effects on one or more body processes (e.g., metabolism) that affects the performance from the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the act of a liver enzyme that Lexapro (escitalopram) is determined by because of its metabolism. This makes more the side-effects of Lexapro.

· Pharmacodynamic: Here, several drugs actually make the same relation to the same organ, thus helping the total, added effect. Example: Lexapro has certain side-effects such as drowsiness and fatigue. Darvocet-N also acts similarly around the brain. Thus, the side-effects of the two medicines are more intense.

Tolerability: A drug might be effective however, not tolerable by all patients. Example: Allergies to a particular drugs in some people. Short-term and long-term tolerability need to be taken into account. Efficacy: A drug is just not equally effective in all patients. As an example, some patients with depression or anxiety disorders experience respite from escitalopram, but there are many that don’t, who therefore need to be prescribed some other anti-depressant. The pace of onset of therapeutic action is a factor to be considered too.

Cost: Cost doesn’t imply the price of acquiring a certain medicine alone. It must also cover the price of treatments for a complication that could arise by using some other drug. Example: Inside a individual that insists on taking alcohol nevertheless has to be treated for depression is generally administered an SSRI drug because these drugs don’t potentiate the results of alcohol, whereas another group of anti-depressants (such as tricyclics) might cause a fresh overuse injury in such patients, which will demand a various and expensive treatment. Therefore, it’s easier to prescribe the more expensive escitalopram rather than a cheaper tricyclic in such patients.

Simplicity of treatment: Most effective mode of administration is preferred. If you have a selection between an injection and oral administration, the second is preferred when the efficacy of the two modes can be compared. Or, local application is chosen over the oral route where possible; e.g., antibiotic treatments for eye infections. Dosage and frequency of administration too are an important factor to make a decision simplicity of treatment.
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