The requirements For choosing Medication For the Patient

SINCE Wwii, medical science has progressed into a stage where competitive medications are for sale to treat precisely the same ailment in several people. This is not almost brands (the trade issue) but generic drugs (the scientific issue). With this report, we shall go through the various factors that decide selecting a particular drug.

Safety: These sub-criteria has to be considered under the criterion of safety:

* Acute therapeutic index: In the event the patient’s condition is acute, how effective is often a particular drug even when they have certain side-effects as long as the acuteness in the condition is lowered? Example: narcotic pain-killers are incredible in healing pain but have the opportunity side-effect of addiction.

* Long-term safety: medication directory could possibly be safe in short-term treatment, so how safe it really is in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but could have undesirable effects in case of prolonged use.

* Drug-drug interaction risk: Medicines are chemicals, and several chemicals respond to produce a different chemical, which has an effect that will harm the individual or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to generate a new condition that warrants separate treatment.

Drug-drug interaction risk is of two sorts:

· Pharmacokinetic: In this kind of drug-drug interaction, two drugs, separate from the other, have certain effects on one or maybe more body processes (e.g., metabolism) that affects the performance in the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the act of a liver enzyme that Lexapro (escitalopram) is dependent upon for the metabolism. This makes more the side-effects of Lexapro.

· Pharmacodynamic: Here, a couple of drugs actually generate the same effect on precisely the same organ, thus increasing the total, added effect. Example: Lexapro has certain side-effects including drowsiness and fatigue. Darvocet-N also acts similarly for the brain. Thus, the side-effects of the drugs are more serious.

Tolerability: A medicine could possibly be effective however, not tolerable by all patients. Example: Allergies to specific drugs in certain people. Short-term and long-term tolerability need to be taken into consideration. Efficacy: A medicine isn’t equally efficient at all patients. For instance, some patients with depression or panic attacks experience reduced escitalopram, but there are several that do not, who therefore need to be prescribed an alternative anti-depressant. The speed of start of therapeutic action is a crucial factor to be regarded as too.

Cost: Cost doesn’t imply the price of buying a certain medicine alone. It should also cover the price of treating a complication that will arise while using an alternative drug. Example: In the individual that insists on taking alcohol yet has to be treated for depression is usually administered an SSRI drug as these drugs don’t potentiate the consequences of alcohol, whereas another band of anti-depressants (including tricyclics) could cause a fresh overuse injury in such patients, which would demand a various and expensive treatment. Therefore, it’s better to prescribe the more costly escitalopram instead of a cheaper tricyclic in such patients.

Simple treatment: The simplest mode of administration is preferred. If there is an alternative between a shot and oral administration, aforementioned is preferred if the efficacy of the modes is the identical. Or, local application is chosen over the oral route where possible; e.g., antibiotic treating eye infections. Dosage and frequency of administration too are an important factor to determine simplicity of treatment.
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