The factors For Selecting Medication For A Patient

SINCE The second world war, medical science has progressed to a stage where competitive medications are available to treat the identical ailment in various people. This isn’t nearly brands (that is a trade issue) but generic drugs (that is a scientific issue). Within this report, we shall go through the various factors that decide selecting a particular drug.

Safety: These sub-criteria must be considered under the criterion of safety:

* Acute therapeutic index: In the event the patient’s condition is acute, how effective is a particular drug even when it has certain side-effects provided that the acuteness from the condition is lowered? Example: narcotic pain-killers are incredible in healing pain but include the opportunity side-effect of addiction.

* Long-term safety: medication may be safe in short-term treatment, so how safe it is in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but could have undesirable effects in the case of prolonged use.

* Drug-drug interaction risk: Prescription medication is chemicals, and lots of chemicals reply to produce a different chemical, which has an effect that will harm the individual or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to produce a new condition that warrants separate treatment.

Drug-drug interaction risk is of two sorts:

· Pharmacokinetic: In this type of drug-drug interaction, two drugs, independent of each other, have certain effects one or more body processes (e.g., metabolism) that affects the performance from the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the action of a liver enzyme that Lexapro (escitalopram) depends on for the metabolism. This makes more the side-effects of Lexapro.

· Pharmacodynamic: Here, 2 or more drugs actually generate the same effect on the identical organ, thus helping the total, added effect. Example: Lexapro has certain side-effects like drowsiness and fatigue. Darvocet-N also acts similarly around the brain. Thus, the side-effects of the medicines are more intense.

Tolerability: A drug may be effective although not tolerable by all patients. Example: Allergies to a particular drugs in some people. Short-term and long-term tolerability need to be looked at. Efficacy: A drug just isn’t equally effective in all patients. By way of example, some patients with depression or anxiety disorders experience rest from escitalopram, but there are several that don’t, who therefore need to be prescribed another anti-depressant. The interest rate of oncoming of therapeutic action is a vital key to be regarded as too.

Cost: Cost does not always mean the expense of acquiring a specific medicine alone. It ought to also cover the expense of treatment of a complication that will arise by using another drug. Example: Inside a one who insists on taking alcohol nevertheless has to be treated for depression is normally administered an SSRI drug as these drugs don’t potentiate the end results of alcohol, whereas another gang of anti-depressants (like tricyclics) might cause a new symptom in such patients, which could have to have a different and expensive treatment. Therefore, it’s safer to prescribe the more expensive escitalopram instead of a cheaper tricyclic such patients.

Simple treatment: The simplest mode of administration is preferred. If there is an option between an injection and oral administration, the latter is preferred in the event the efficacy of the modes is analogous. Or, local application is chosen over the oral route where possible; e.g., antibiotic treatment of eye infections. Dosage and frequency of administration too are a key point to make a decision simplicity of treatment.
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