The factors For choosing Medication To get a Patient
SINCE The second world war, medical science has progressed to some stage where competitive medications are around for treat precisely the same ailment in several people. This is simply not just about brands (which is a trade issue) but generic drugs (which is a scientific issue). With this report, we shall consider the various factors that decide the selection of a specific drug.
Safety: The next sub-criteria must be considered underneath the criterion of safety:
* Acute therapeutic index: If the patient’s condition is acute, how effective is a particular drug even if it’s certain side-effects so long as the acuteness with the condition is lowered? Example: narcotic pain-killers are amazing in healing pain but feature the potential side-effect of addiction.
* Long-term safety: drug directory might be safe in short-term treatment, so how safe it really is in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but can have undesirable effects in the case of prolonged use.
* Drug-drug interaction risk: Drugs are chemicals, and several chemicals reply to create a different chemical, that have an effect that will harm the person or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to make a new condition that warrants separate treatment.
Drug-drug interaction risk is of two sorts:
· Pharmacokinetic: In this kind of drug-drug interaction, two drugs, outside of the other person, have certain effects using one or maybe more body processes (e.g., metabolism) that affects the performance with the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the act of a liver enzyme that Lexapro (escitalopram) is determined by for the metabolism. This will cause a rise in the side-effects of Lexapro.
· Pharmacodynamic: Here, a couple of drugs actually produce the same influence on precisely the same organ, thus helping the total, added effect. Example: Lexapro has certain side-effects including drowsiness and fatigue. Darvocet-N also acts similarly about the brain. Thus, the side-effects of the two medicines are more intense.
Tolerability: A medicine might be effective and not tolerable by all patients. Example: Allergies to particular drugs in certain people. Short-term and long-term tolerability need to be taken into consideration. Efficacy: A medicine is not equally good at all patients. By way of example, some patients with depression or panic attacks experience reduced escitalopram, but there are many who don’t, who therefore need to be prescribed some other anti-depressant. The interest rate of oncoming of therapeutic action is a factor to be looked at too.
Cost: Cost does not necessarily mean the price tag on acquiring a specific medicine alone. It will also cover the price tag on treatment of a complication that will arise while using some other drug. Example: Within a individual who insists on taking alcohol and yet needs to be treated for depression is normally administered an SSRI drug as these drugs don’t potentiate the effects of alcohol, whereas another band of anti-depressants (including tricyclics) could cause a fresh symptom in such patients, which may need a different and expensive treatment. Therefore, it’s easier to prescribe the more expensive escitalopram instead of a cheaper tricyclic in this patients.
Simple treatment: The simplest mode of administration is preferred. When there is a choice between a shot and oral administration, the latter is preferred in the event the efficacy of the two modes is analogous. Or, local application is preferred to the oral route where possible; e.g., antibiotic treatment of eye infections. Dosage and frequency of administration too are a key point to determine simple treatment.
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